Multiple instances per host?

I have several large hosts (36 cores (72 w/ HT), 512GB RAM, 6TB SSDs over 8 disks per host), all on a local 10Gbps network. Does it make sense to run multiple instances of Cockroach on each node (given the disclaimer of host failure impacting many instances)? or will a single instance scale to the CPU and memory on the systems? If I should use multiple, how many would make sense?

Thank you.